Make a vision as TREATMENT FOR ALL ..!!
Join on April 17 to raise awareness about HEMOPHILIA and other inherited bleeding disorders. Every in 1,000 people has a bleeding disorder. Together we can change that.
WORLD HEMOPHILIA DAY provides an opportunity to talk to your family and friends, colleagues, and caregivers to raise awareness and increase support for those living with an inherited bleeding disorder.
What is Bleeding Disorder?
Bleeding disorders are a group of disorders that share the inability to form a proper blood clot.
A bleeding disorder is a condition that affects the clotting process.
The clotting process, also known as coagulation, changes blood from a liquid to a solid.
When you’re injured, your blood normally begins to clot to prevent a massive loss of blood.
The body produces 13 clotting factors.
Some disorders can drastically increase the amount of blood leaving your body.
They are characterized by extended bleeding after injury, surgery, trauma or menstruation.
Improper clotting can be caused by defects in blood components such as platelets and/or clotting proteins, also called clotting factors.
If any of them are defective or deficient, blood clotting is affected; a mild, moderate or severe bleeding disorder can result.
Some bleeding disorders, such as hemophilia, can be inherited or acquired.
Others can occur from such conditions as Anemia, Liver Cirrhosis, HIV, Leukemia and Vitamin K Deficiency.
They also can result from certain medications that thin the blood, including Aspirin, Heparin and Warfarin.
Sometimes, certain conditions prevent blood from clotting properly, which can result in heavy or prolonged bleeding.
A Royal Disease
Hemophilia is sometimes referred to as “the royal disease,” because it affected the royal families of England, Germany, Russia and Spain in the 19th and 20th centuries.
Queen Victoria of England, who ruled from 1837-1901, is believed to have been the carrier of hemophilia B, or factor IX deficiency. She passed the trait on to three of her nine children. Her son Leopold died of a hemorrhage after a fall when he was 30. Her daughters Alice and Beatrice passed it on to several of their children. Alice’s daughter Alix married Tsar Nicholas of Russia, whose son Alexei had hemophilia. Their family’s entanglement with Rasputin, the Russian mystic, and their deaths during the Bolshevik Revolution have been chronicled in several books and films.
Hemophilia was carried through various royal family members for three generations after Victoria, later disappeared.
What causes bleeding disorders?
For blood to clot, your body needs blood proteins called clotting factors and blood cells called platelets.
The clotting factors then come together to form a fibrin clot. This keeps the platelets in place and prevents blood from flowing out of the blood vessel.
In people with bleeding disorders, however, the clotting factors or platelets don’t work the way they should.
The majority of bleeding disorders are inherited, which means they’re passed from a parent to their child.
However, some disorders may develop as a result of other medical conditions, such as liver disease.
Bleeding disorders may also be caused by:
a low red blood cell count
a vitamin K deficiency
side effects from certain medications
Medications that can interfere with the clotting of the blood are called anticoagulants.
Types of disorder:
There are numerous different bleeding disorders, but the following are the most common ones:
Hemophilia A and B are conditions that occur when there are low levels of clotting factors in your blood. It causes heavy or unusual bleeding into the joints. Though hemophilia is rare, it can have life-threatening complications.
Factor II, V, VII, X, or XII deficiencies are bleeding disorders related to blood clotting problems or abnormal bleeding problems.
Von Willebrand's Disease is the most common inherited bleeding disorder. It develops when the blood lacks von Willebrand factor, which helps the blood to clot.
Symptoms:
Easy bruising
Bleeding gums
Heavy bleeding from small cuts or dental work
Unexplained nosebleeds
Heavy menstrual bleeding
Bleeding into joints
Excessive bleeding following surgery
Treatment
Treatment for bleeding disorders varies, depending on the condition and its severity.
For some bleeding disorders, there are the clotting factor concentrates that can be infused prophylactically or on-demand at home, to prevent or treat bleeds.
For other bleeding disorders, there are Topical Products, Nasal Sprays and Fresh Frozen Plasma, which is administered in a hospital setting.
Though treatments can’t cure bleeding disorders, they can help relieve the symptoms associated with certain disorders.
These treatments include:
Iron Supplementation
Blood Transfusion
Other Treatments
Hope our content will create awareness for Hemophilia and other inherited bleeding disorders on WORLD HEMOPHILIA DAY.
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